Година XXIV, Книжка 3, 2015<<Архив>>

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ПОСТНОРМАЛНАТА НАУКА – БЕЛЕЗИ И НОВИ ТЕНДЕНЦИИ

С преодоляването на блоковото разделение на света и науката възстанови своята глобална цялост. Процесите на диференциация на науката се замениха от процеси на интеграция и заличаване на границите между частните научни дисциплини; на преден план в научните изсл...

Б. В. Тошев

post-normal science, integration, 3P-model, scientometrics, index of Hirsch

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SYNTHESIS OF FLUORINATED HYDROXYCINNAMOYL DERIVATIVES OF ANTI-INFLUENZA DRUGS AND THEIR BIOLOGICAL ACTIVITY

The emergence of a novel pandemic influenza A (H1N1) strain in 2009 is an evident mark for the unremitting risk of respiratory viral diseases. Influenza outbreaks and development of desease and could be overcome by use of vaccines and antivirals. Currently, cli...

Boyka Stoykova, Maya Chochkova, Galya Ivanova, Luchia Mukova, Nadya Nikolova, Lubomira Nikolaeva-Glomb, Pavel Vojtíšek, Tsenka Milkova, Martin Štícha, David Havlíček

M2 ion channel blockers, neuraminidase inhibitors, N-hydroxycinnamoyl fluorinated amino acids amides

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SYNTHESIS AND ANTIVIRAL ACTIVITY OF SOME AMINO ACIDS DERIVATIVES OF INFLUENZA VIRUS DRUGS

A series of new rimantadine (RS)-1-(1-adamantyl)ethanamine) analogues with some amino acids (alanine, valine, phenylalanine) have been synthesized and their antiviral activity against influenza A virus has been studied. Among the tested compounds the moderat...

Radoslav Chayrov, Vesela Veselinova, Vasilka Markova, Luchia Mukova, Angel Galabov, Ivanka Stankova

Rimantadine, amino acids, influenza virus

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NEW DERIVATIVES OF OSELTAMIVIR WITH BILE ACIDS

Several derivatives of oseltamivir with bile acids (cholic, deoxycholic and chenodeoxycholic acids) were prepared, using N, N dicyclohexylcarbodiimide (DCC) as coupling reagent. The chemical modifications were made in order to enhance the bioavailability...

Kiril Chuchkov, Silvia Nakova, Lucia Mukova, Angel Galabov, Ivanka Stankova

oseltamivir, bile acids, Iinfluenza virus

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MONOHYDROXY FLAVONES. PART III: THE MULLIKEN ANALYSIS

The purpose of this article is to compare Mulliken charges in monohydroxy flavones in order to assess the intramolecular reasons determining the electron density distribution and reactivity in all ten isomers. What would also be estimated is the role of the po...

Maria Vakarelska-Popovska, Zhivko Velkov

Mulliken population analysis, monohydroxy flavones.

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LEU-ARG ANALOGUES: SYNTHESIS, IR CHARACTERIZATION AND DOCKING STUDIES

Leu-Arg is a kyotorphin receptor antagonist. It is very important to control antinociception and this could be achieved by modifications in agonist’s or antagonist’s molecules. Two analogues of Leu-Arg were synthesized, their IR- spectral characteristics we...

Tatyana Dzimbova, Atanas Chapkanov, Tamara Pajpanova

kyotorhin, IR, docking, Mu-opioid receptor, GOLD

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SYNTHESIS OF 2-FLUOROMETHYL-7(ARYLSULFANYLMETHYL) NAPHTHALENES

Starting from the readily available 2,7-bis(bromomethyl)naphthalene, two 2-fluoromethyl-7-(arylsulfanylmethyl) naphthalene derivatives were prepared in four steps. It was found that direct, partial treatment of 2,7-bis(bromomethyl)naphthalene with thiopheno...

Jane Bogdanov

2-fluoromethyl-7-(phenylsulfanylmethyl)naphthalene, 2-fluoromethyl-[(4-bromophenyl)sulfanylmethyl]naphthalene, synthesis

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INVESTIGATION OF THE ETHERIFICATION PROCESS UNDER MODEL MIXTURE

The composition of fuel has changed tremendously, and also engine technology has played an important role in improvements related to combustion. At the same time the number of motor vehicles has increased rapidly world-wide and the cut-backs on harmful emiss...

Yordanka Tasheva

etherification, gasoline, model mixture, additive

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MODIFIED QUECHERS METHOD FOR DETERMINATION OF METHOMYL, ALDICARB, CARBOFURAN AND PROPOXUR IN LIVER

N-Methyl carbamates insecticides are widely used in homes, gardens, and agriculture. Unfortunately, traces of them can further be found into animal tissues, milk, honey, eggs, etc. Therefore, food safety is an integral part of the EU policy for protecti...

I. Stoykova, T. Yankovska-Stefenova, L.Yotova, D. Danalev

QuEchERS, pesticides, N-methyl carbamates, HPLC

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ORGANIC COMPOUNDS AS INHIBITORS FOR MILD STEEL IN \(\mathbf{1} \mathrm{M} \mathrm{H}_{2} \mathrm{SO}_{4}\)

The inhibitory effect of two organic compounds has been studied: 2-(4-cyanophenyl)-1-oxo-1H-inden-3-yl acetate and 2-(4-fluorophenyl)-1-oxo-1Hinden-3-yl acetate on samples of Steel 3 in \(0.1 \mathrm{M} \mathrm{H}_{2} \mathrm{SO}_{4}\). Using gravimetric ana...

T. Haralanova, C. Girginov

corrosion, steel 3, organic compounds, inhibitors

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MICROBIAL X CELLS – INNOVATIVE MULTIPURPOSE BIOELECTROCHEMICAL SYSTEMS

This paper reviews the state-of-the art of the bioelectrochemical systems (BESs), utilizing whole living cells as biocatalysts, which has been intensively developed during the last decade. The principles of operation, specificity and potential applications...

Mario Mitov, Yolina Hubenova

bioelectrochemical systems, microbial fuel cells, microbial electrolysis cells, practical application

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LACTOBACILLUS PLANTARUM AC 11S AS A BIOCATALYST IN MICROBIAL ELECYTOLYSIS CELL

This study demonstrates for the first time the utilization of the bacterial strain <i>Lactobacillus plantarum</i> АС 11S as a biocatalyst in microbial electrolysis cell (MEC). The microorganisms were preliminarily immobilized on carbon felt, used as a bioano...

Elitsa Chorbadzhiyska, Yolina Hubenova, Sophia Yankova, Dragomir Yankov, Mario Mitov

microbial electrolysis cell, <i>Lactobacillus plantarum</i> АС 11S, biocatalyst, hydrogen production

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Pd-Au DEPOSITES ON NI-FOAM AS ANODIC ELECTROCATALYSTS FOR DIRECT BOROHYDRIDE FUEL CELL

In this study, Pd and Au were deposited on Ni-foam and examined as electrocatalysts for borohydride electrooxidation. The Pd-Au deposits were developed by co-deposition from mixed solutions of Pd\(^{2+}\) and Au\(^{3+}\)with different ratios of both metals....

Georgi Hristov, Elitsa Chorbadzhiyska, Mario Mitov

Pd-Au catalyst, borohydride electrooxidation, direct borohydride fuel cell

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SEDIMENT MICROBIAL FUEL CELLS AS POWER SOURCES FOR SMALL ELECTRICAL CONSUMERS

Sediment Microbial Fuel Cells (SMFCs) are considered as reliable devices for conversion of the chemical energy of organic matter, containing in aquatic sediments, into electrical energy. In this study, nine freshwater SMFCs were connected in series or in pa...

Ivo Bardarov, Yolina Hubenova, Mario Mitov

sediment microbial fuel cell, energy conversion, bioelectrochemical power sources, power management system

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SOLID PHASE EXTRACTION OF Au(III) USING SILICA GEL MODIFIED WITH 4-AMINOANTIPYRINE SCHIFF BASES

The degree of extraction of Au (III) from hydrochloric acid solutions on 4-aminoantipyrine Schiff bases modified silica gel was studied. Quantitative sorption of Au (III) on the surface of the sorbent containing azomethine group was achieved in the presence...

P. Petrova, I. Karadjova, M. Chochkova, I. Dakova

solid phase extraction; noble metals; 4-aminoantipyrine schiff base

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INDUCTIVELY COUPLED PLASMA OPTICAL EMISSION SPECTROSCOPY – DETERMINATION OF RARE EARTH AND PLATINUM GROUP OF ELEMENTS

The economic importance of rare earth elements and platinum group of elements has led to the development of analytical methods, which have to ensure their accurate quantification in different type of samples. Radial viewing 40.68 MHz inductively coupled plas...

N. Velitchkova, P. Petrova, S. Velichkov, N. Daskalova

ICP-OES; rare earth elements; platinum group element; matrix effects; detection limits

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STUDYING THE PROCESS OF DEPOSITION OF ANTIMONY WITH CALCIUM CARBONATE

Industrial production of copper solutions, in addition to the basic components (Cu, Ni), contain undesirable impurities which include arsenic and antimony. The process of withdrawal of antimony in copper electrolyte with calcium carbonate, which is present in...

K. B. Omarov, Z. B. Absat, S. K. Aldabergenova, A. B. Siyazova, N. J. Rakhimzhanova, Z. B. Sagindykova

copper production, electrolyte, antimony, calcium carbonate, copper, calcium antimonate